AMEX:PRW











Watch Pro-Pharmaceuticals' Senior Executives Featured on PBS' "Wealth & Wisdom"

    What's New
07/15/08

Pro-Pharmaceuticals Has Requested a Pre-IND Meeting with the U.S. Food and Drug Administration.

Introduction of Oxygen-based Product (EZ-646) to the Company’s Galactomannan-C (DAVANAT®) with 5-FU to Treat All Solid Tumors, especially Head & Neck, Breast & Colorectal.

This Study is in Addition to the Company’s Ongoing Phase ll Clinical Trials of DAVANAT® with 5-FU to Treat Colorectal & Biliary Cancer.

07/11/08

Pro-Pharmaceuticals' Senior Executives to Be Featured on PBS' "Wealth & Wisdom".

Financial Television Program to Air the Exclusive Interview.

07/10/08

Pro-Pharmaceuticals Appoints Noted Pioneer in Liver Diseases, Scott L. Friedman, M.D., to Scientific Advisory Board.

Current Chief of the Division of Liver Diseases at Mount Sinai School of Medicine and President-elect of the American Association for the Study of Liver Diseases.

07/09/08

Pro-Pharmaceuticals and Sanghyon Chemical Ink Historic Agency Agreement.

Korean Food & Drug Administration Registration of Lead Compound Candidate DAVANAT® in Korea.

Sales & Marketing Support with Licensing & Distribution Plans.

06/25/08

Pro-Pharmaceuticals' Executives Contribute to Definitive Book on Galectins.

Pro-Pharmaceuticals’ DAVANAT® Targets Galectin Receptorson Cancer Cells.

05/21/08

Pro-Pharmaceuticals Issues Letter to Shareholders.

05/20/08

Pro-Pharmaceuticals Announces Submission of Drug Master File for DAVANAT® to FDA.

Company Completes an Important Step in NDA Plan for DAVANAT®.

05/20/08

Pro-Pharmaceuticals Receives Amex Non-Compliance Notice.

05/19/08

Pro-Pharmaceuticals Collaborates with Biocancell Therapeutics to Deliver siRNA Through IV Administration.

DAVANAT® and BC-819 Target Cancer Cells.

05/15/08

Pro-Pharmaceuticals Reports First Quarter Results.

05/01/08

PRO-PHARMACEUTICALS UPDATES NDA FILING FOR DAVANAT®.

Follows FDA Guidance to Provide Chemistry, Manufacturing & Controls Data.

04/14/08

Pro-Pharmaceuticals Announces Change in Auditors.

04/07/08

Pro-Pharmaceuticals Announces Commercialization Plans For DAVANAT® With YIACO Medical.

YIACO Medical Represents 80 Health Care Companies and Serves 18 Countries with a Population of 400 Million.

03/28/08

Pro-Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Financial Results.

The Company Plans to File a New Drug Application with the FDA for DAVANAT®.

03/24/08

Pro-Pharmaceuticals Announces DAVANAT® Regimen Approved to Treat Breast Cancer Patient.

03/03/08

Pro-Pharmaceuticals DAVANAT® Extends Median Survival 6.7 Months for End-Stage Colorectal Cancer Patients After All Other Treatments Failed.

02/28/08

Pro-Pharmaceuticals Closes Financing.

02/15/08

Pro-Pharmaceuticals Enters into Definitive Agreements for $3.775 Million Financing.

02/11/08

New Data Shows DAVANAT® Extends Survival of End-Stage Colorectal Cancer Patients More Than 6 Months.

Pro-Pharmaceuticals Tracks Patients After Phase ll Trial: Two Patients Survived More Than 2 Years.

02/08/08

Pro Pharmaceuticals Teams With UMass-Lowell On Target Drug Therapy.

source:
Nanowerk News
The Daily Collegian (Matt Sheehan)

02/06/08

Pro-Pharmaceuticals Notes That Shelf Registration is Effective.

01/31/08

Pro-Pharmaceuticals to Present Corporate Update at Russ Trading Investor Meeting in Tempe, Arizona, and Red Chip Small Cap Conference in Scottsdale.

01/29/08

Pro-Pharmaceuticals Phase ll Trial Shows DAVANAT® Improves Median Progression Free Survival with Fewer Side Effects as Compared to Recent Similar Studies.

01/29/08

Pro-Pharmaceuticals Files $10 Million Shelf Registration.

12/28/07

Pro-Pharmaceuticals Plans to Present a Corporate Update at the Red Chip Small Cap Investor Conference.

12/19/07

Pro-Pharmaceuticals Selects SAFC®, a Division of SIGMA- ALDRICH™, to Submit a Drug Master File.

An Important Step in the NDA Approval Process for DAVANAT®.

12/12/07

Pro-Pharmaceuticals Enters Research Collaboration with University of Massachusetts Lowell.

12/06/07

Pro-Pharmaceuticals & Brigham and Women's Hospital Announce New Kidney Fibrosis Research Collaboration.

11/14/07

Pro-Pharmaceuticals Reports Third Quarter Results.

10/30/07

Pro-Pharmaceuticals to Present:
“Advancing Drugs Through Glycoscience®”
at Rodman & Renshaw’s Healthcare Conference.

10/17/07

Pro-Pharmaceuticals Novel Carbohydrate Compounds Reverse Liver Fibrosis in Pre-clinical Studies.

10/11/07

Pro-Pharmaceuticals Reports 43% Response Rate in Colorectal Trial; No Hematological or Gastrointestinal Serious Adverse Events Reported.

10/02/07

Pro-Pharmaceuticals Names Anthony Squeglia Chief Financial Officer; Steven Schubert Vice President Finance.

09/24/07

Pro-Pharmaceuticals Names Theodore Zucconi, Ph.D., President; Nominated to the Board of Directors.

09/14/07

Amex Accepts Pro-Pharmaceuticals Plan of Compliance.

08/20/07

Pro-Pharmaceuticals’ Sponsored Symposium on Galectins Begins Today as Part of the American Chemical Society’s 234th Annual Meeting & Exposition.

Proposed Mechanism of Action for the Company’s Lead Compound DAVANAT®: Targets Galectin Receptors on Cancer Cells.

08/16/07

Pro-Pharmaceuticals Announces “Compassionate Use” IND for DANANAT® to Treat Biliary Cancer Patient.

08/10/07

Pro-Pharmaceuticals Reports Second Quarter Results.

08/03/07

Pro-Pharmaceuticals Retains Camargo Pharmaceutical to Provide Strategic Regulatory Support for 505(b)(2) Submissions.

07/27/07

Pro-Pharmaceuticals Issues Corporate Update.

07/25/07

Pro-Pharmaceuticals Announces Boston Medical Center Dosing Patients with DAVANAT® in Advanced Biliary Cancer Trial.

07/24/07

Pro-Pharmaceuticals Submits Plan of Compliance to Amex.

07/23/07

Pro-Pharmaceuticals Enters Research Agreement with Global Bio-pharmaceutical Company.

07/09/07

Pro-Pharmaceuticals Updates Progress
Of Clinical Trials & DAVANAT® 505 (B)(2) Filings.

Phase ll Colorectal Cancer Patients Stabilized Up to 7 Months; Phase ll Biliary Cancer Patients Stabilized Up to 5 Months.

Patients Experience No Increase in Drug-Related Toxicity & Reduced Side Effects with Increased Exposure to 5-FU & AVASTIN®.

Plans to Submit Manufacturing Data for DAVANAT® 505 (b)(2) Filings to the FDA this Year; No Additional Toxicity or Clinical Trial Data Needed.

07/02/07

Pro-Pharmaceuticals Terminates Financing Agreement.

The Company is Evaluating other Financing Alternatives.

06/26/07

Pro-Pharmaceuticals Reports Receipt of Notice from Amex.

06/19/07

Pro-Pharmaceuticals Enters into Definitive Agreements for a $2.7 Million Financing.

06/14/07

Pro-Pharmaceuticals to Sponsor American Chemical Society’s Special Symposium on Galectins.

Proposed Mechanism of Action for the Company’s Lead Compound DAVANAT®: Binds to Galectin Receptors on Cancer Cells.

06/11/07

Pro-Pharmaceuticals Submits Data to Begin a
505 (b)(2) Filing with the FDA for a New Formulation of Irinotecan to be Co-administered with DAVANAT® as a Functional Excipien.

Irinotecan is a Leading Chemotherapy Drug in Colorectal Cancer Treatment.

05/17/07

Pro-Pharmaceuticals to Present Abstract at the International Society of Oncodevelopmental Biology and Medicine Conference.

05/15/07

Pro-Pharmaceuticals Reports First Quarter Results.

05/14/07

Pro-Pharmaceuticals Issues Clinical Trial Update.

05/08/07

Pro-Pharmaceuticals to Present and Webcast
at Rodman & Renshaw’s Global Healthcare Conference.

04/30/07

Pro-Pharmaceuticals and Digna Biotech Sign Agreement to Apply DAVANAT® with Novel Drugs to treat Hepatitis C.

04/17/07

Pro-Pharmaceuticals Issues Corporate Update.

04/16/07

S. Colin Neill Nominated to Pro-Pharmaceuticals Board of Directors.

04/12/07

Pro-Pharmaceuticals Plans to Submit a New Drug Application for DAVANAT®, as a Functional Excipient, with 5-FU to Treat Cancer.

04/11/07

Pro-Pharmaceuticals Receives Letter from the FDA for New Drug Application for DAVANAT®/ 5-FU.

FDA Considers DAVANAT® a “Novel” Excipient.

04/04/07

Pro-Pharmaceuticals Announces Tampa General Hospital Dosing Patients with DAVANAT®/5-FU in Phase II, First Line, Advanced Biliary Cancer Clinical Trial.

04/02/07

Pro-Pharmaceuticals Reports Fourth Quarter and Full Year 2006 Financial Results.

Annual Shareholders Meeting Scheduled for May 24th.

03/21/07

Pro-Pharmaceuticals Restructures Convertible Debentures.

02/28/07

Pro-Pharmaceuticals Submits Orphan Drug Status Application to European Medicines Agency.

Co-administration of DAVANAT® with 5-FU to Treat Cholangiocarcinoma.

02/27/07

Pro-Pharmaceuticals Announces Third Site Dosing Patients with DAVANAT® in Phase ll, First Line, Colorectal Cancer Clinical Trial.

02/23/07

Pro-Pharmaceuticals Meeting Scheduled with the FDA.

April 11th Meeting to Discuss NDA Submission for Co-administration of DAVANAT® with 5-FU to Treat Cancer Patients.

02/20/07

Pro-Pharmaceuticals Collaborates with Chemwerth to Scale Up Production of DAVANAT® for Initial Marketing Needs.

Chemwerth Scales Up DAVANAT® to 100 Kilos per Batch.

02/16/07

Pro-Pharmaceuticals to Account for Warrants as Liabilities from 2003 and 2004 Equity Finance Transactions.

Liability Treatment Does Not Change Operating Expenses or Cash Position.

02/12/07

Pro-Pharmaceuticals Requests Meeting with the FDA to Discuss New Drug Application for
Co-administration of DAVANAT® with 5-FU to Treat Cancer Patients.

5-FU is one of the most widely used chemotherapy drugs in the world.

02/07/07

Pro-Pharmaceuticals’ Begins Process of New Drug Application Submission with the FDA for Co-administration of DAVANAT® with 5-FU
in Cancer Patients.

01/23/07

Pro-Pharmaceuticals Announces Dosing of Patients with DAVANAT® in Phase II, First Line, Advanced Biliary Cancer Clinical Trial.

12/22/06

Pro-Pharmaceuticals Provides Corporate Update of 2006 Achievements and 2007 Objectives.

12/20/06

Pro-Pharmaceuticals Appoints Dr. James Gourzis to its Board of Directors.

12/19/06

Pro-Pharmaceuticals Signs Agreement with CESAR to Expand Recruitment of Patients for the Phase ll Biliary Cancer Trial.

11/27/06

Pro-Pharmaceuticals Announces Dosing of Patients with DAVANAT® in Phase II, First Line, Colorectal Cancer Clinical Trial.

11/21/06

Rodman & Renshaw, LLC Initiates Research Coverage on Pro-Pharmaceuticals.

11/13/06

Pro-Pharmaceuticals Reports Third Quarter 2006 Results.

11/01/06

Pro-Pharmaceuticals to Present a Corporate Update at Rodman & Renshaw Healthcare Conference; ''Advancing Drugs Through Glycoscience'' Presentation to be Webcast.

10/30/06

Pro-Pharmaceuticals to Present a Corporate Update at MASS Opps: a Biotechnology Investment Conference.

10/17/06

Pro-Pharmaceuticals to Present at BIO Investor Forum.

09/28/06

Pro-Pharmaceuticals Announces Cash Payment of Debentures & Clinical Trial Progress.

08/30/06

Pro-Pharmaceuticals Updates Clinical Trials Progress.

08/14/06

Pro-Pharmaceuticals Reports Second Quarter 2006 Results.

07/25/06

Pro-Pharmaceuticals Files Phase II Clinical Trial Protocol for First Line Treatment of Colorectal Cancer Patients.

Regimen Includes DAVANAT® with Avastin(R), 5-FU & Leucovorin.

06/05/06

Pro-Pharmaceuticals' Abstract Published in ASCO Annual Meeting Proceedings.

Company Provides Clinical Trial Update.

05/31/06

Pro-Pharmaceuticals' Executives Contribute to New Book ''Carbohydrate Drug Design'' Published by American Chemical Society.

05/24/06

Pro-Pharmaceuticals & Mount Sinai School of Medicine Announce New Liver Fibrosis Research Collaboration.

05/22/06

Pro-Pharmaceuticals Reports First Quarter 2006 Financial Results.

Annual Shareholders Meeting Scheduled for May 25th.

05/09/06

Pro-Pharmaceuticals to Present Corporate Update at Rodman & Renshaw Global Healthcare Conference.

''Advancing Drugs Through Nanotechnology Glycoscience'' Presentation to be Available via Webcast.

05/08/06

Pro-Pharmaceuticals Retains Dr. James T. Gourzis to Provide Clinical Management & Strategic Development of Its Europe-Based Phase III Colorectal Cancer Trial.

04/10/06

Dr. Henry Esber Nominated to Pro-Pharmaceuticals Board Of Directors.

04/07/06

Pro-Pharmaceuticals' CEO to Present Corporate Update at BIO Annual Convention.

04/05/06

Pro-Pharmaceuticals Reports Preliminary Data Shows an Objective Partial Tumor Response in Phase II Colorectal Cancer Trial Evaluating DAVANAT® with 5-FU.

03/30/06

Pro-Pharmaceuticals Completes Patient Enrollment in Stage 1 of Phase II Colorectal Cancer Trial Evaluating DAVANAT® with 5-FU.

03/23/06

Pro-Pharmaceuticals to Present Corporate Update at Russ Trading Hosted Event in Scottsdale, Arizona.

03/22/06

Pro-Pharmaceuticals Featured on ''American Scene'' Financial Talk Radio Show.

03/17/06

Pro-Pharmaceuticals' Abstract Accepted for Publication in ASCO Annual Meeting Proceedings.

03/16/06

Pro-Pharmaceuticals Continues to Strengthen
Intellectual Property Portfolio.

Fifth U.S. Patent Covers Co-administration of a Carbohydrate with a Chemotherapy Agent to Treat Cancer.

03/14/06

Pro-Pharmaceuticals' CEO Featured on Wall Street Reporter.

03/10/06

Pro-Pharmaceuticals Reports Unaudited Fourth Quarter and Full Year 2005 Financial Results.

03/02/06

Pro-Pharmaceuticals to Present Abstract & Poster at Mass Biotechnology Council Discovery Day Symposium.

02/24/06

Pro-Pharmaceuticals Presents Phase II/III Clinical Trials at the Central European Society for Anti-Cancer Drug Research Conference.

02/15/06

Pro-Pharmaceuticals Announces $10 Million Financing.

02/02/06

Pro-Pharmaceuticals Receives 'Compassionate Use' IND for Use of DAVANAT®/5-FU to Treat Another Patient with Cholangiocarcinoma.

01/23/06

Scientist’s passion for pharmaceutical innovation driving cancer drug trials.

01/13/06

Pro-Pharmaceuticals Announces the Appointment of Anatole Klyosov, Ph.D., D.Sc. as Chief Scientist.

Company Continues to Strengthen Intellectual Property Portfolio—Receives New U.S. Patent for the Delivery of a Therapeutic Agent to Reduce Toxicity.

12/13/05

Pro-Pharmaceuticals Announces Two International Clinical Sites in Colorectal Cancer Trial of DAVANAT®/5-FU.

12/09/05

Pro-Pharmaceuticals Issues Corporate Update.

Outlines Achievements and Key Clinical Milestones.

11/11/05

Pro-Pharmaceuticals to Present at Annual Glycobiology Conference.

Targeting Tumor Lectins, DAVANAT® Shows Promising Results in Phase I Trial with 5-FU Refractory Patients.

11/10/05

Pro-Pharmaceuticals Reports Third Quarter Results

11/07/05

Pro-Pharmaceuticals Receives Clearance from EMEA to Initiate International Phase III Colorectal Cancer Clinical Trial.

11/02/05

Pro-Pharmaceuticals to Present at Techvest Healthcare Conference.

10/25/05

Pro-Pharmaceuticals to Present at Mass Opps
Biotech Investor Conference.

10/14/05

Pro-Pharmaceuticals Reports Enrollment Progress in Phase II Colorectal Cancer Trial with DAVANAT®/5-FU.

10/06/05

Pro-Pharmaceuticals Announces Final Phase I Results.

Pharmacokinetics Analysis Indicates 5-FU, in Combination with DAVANAT®, Remains Significantly Longer in the Bloodstream of Cancer Patients, Potentially Increasing 5-FU’s Efficacy while Lowering Toxicity.

09/20/05

Pro-Pharmaceuticals to Present New DAVANAT® Data at the International Society of Oncodevelopmental Biology and Medicine Conference.

09/13/05

Pro-Pharmaceuticals Files Phase ll Protocol for DAVANAT®/5-FU in First Line Cholangiocarcinoma Study.

“Compassionate Use” Patient Continues to Respond Well after 10 Months of Treatment with DAVANAT®/5-FU.

08/25/05

Pro-Pharmaceuticals Announces Dosing of Patient with DAVANAT®/5-FU in Phase II Colorectal Cancer Trial at Ochsner Cancer Institute.

08/05/05

Pro-Pharmaceuticals Reports Second Quarter Results.

07/28/05

Pro-Pharmaceuticals Announces Termination of SEC Investigation.

07/21/05

Vista Partners Initiates Research Coverage of Pro-Pharmaceuticals.

07/07/05

Pro-Pharmaceuticals Receives New U.S. Patent for the Delivery of a Chemotherapeutic Agent to Reduce Toxicity.

New Patent Strengthens the Company’s Intellectual Property Portfolio.

06/27/05 PRO-PHARMACEUTICALS ADDED TO THE NEW RUSSELL MICROCAP INDEX.
05/19/05 PRO-PHARMACEUTICALS ANNOUNCES DOSING OF CANCER PATIENT with DAVANAT®/5-FU in a PHASE II CLINICAL TRIAL at HEMATOLOGY-ONCOLOGY ASSOCIATES of TREASURE COAST
05/17/05 PRO-PHARMACEUTICALS’ PHASE II COLORECTAL CANCER TRIAL OF
DAVANAT®/5-FU POSTED TO CLINICAL TRIALS.GOV WEBSITE

Metastatic Colorectal Cancer Trial is Recruiting Patients for Third- or Fourth-Line Therapy
05/16/05 PRO-PHARMACEUTICALS’ PHASE I DATA SHOW DAVANAT®/5-FU WELL-TOLERATED IN CANCER PATIENTS WITH ADVANCED SOLID TUMORS

Disease Stabilized in 54% of Patients with Measurable Disease; 60% Stabilized at Highest Dose Level; 71% Received Additional Cycles
05/13/05 Pro-Pharmaceuticals Reports First Quarter Results
05/12/05 PRO-PHARMACEUTICALS RECEIVES “COMPASSIONATE USE” IND FOR USE OF DAVANAT®/5-FU WITH A PATIENT WHO HAS CHOLANGIOCARCINOMA WITH LIVER METASTASES
05/09/05 PRO-PHARMACEUTICALS ANNOUNCES DOSING OF CANCER PATIENT with DAVANAT®/5-FU in a PHASE II CLINICAL TRIAL at MEDICAL ONCOLOGY & HEMATOLOGY, P.C.
05/02/05 Pro-Pharmaceuticals to Present at Techvest Global Healthcare Conference
04/27/05 Research Analyst Report on Pro-Pharmaceutials
04/08/05 Pro-Pharmaceuticals Reports Fourth Quarter and Full Year 2004 Results

Annual Shareholders Meeting Scheduled for May 25th
03/22/05 Pro-Pharmaceuticals’ Lead Compound DAVANAT® Enhances Anti-Tumor Activity of Avastin™/5-FU in Pre-Clinical Studies

Data Presented at Glycomics & Carbohydrates Conference
03/03/05 PRO-PHARMACEUTICALS’ FINAL PHASE l ABSTRACT ACCEPTED FOR PUBLICATION IN ASCO ANNUAL MEETING PROCEEDINGS
02/24/05 PRO-PHARMACEUTICALS ENGAGES WORLDCARE CLINICAL TO ENHANCE AND ACCELERATE THE PHASE II TRIAL
02/14/05 PRO-PHARMACEUTICALS POSTS ASCO DATA TO ITS WEBSITE

DAVANAT®/5-FU Well Tolerated; Dose Limiting Toxicity Not Reached; Disease Stabilized in 45% of Patients
02/11/05 PRO-PHARMACEUTICALS NAMES CARL LUEDERS CHIEF FINANCIAL OFFICER
01/27/05 PRO-PHARMACEUTICALS’ ASCO DATA SHOW DAVANAT®/5-FU WELL-TOLERATED IN PATIENTS WITH ADVANCED CANCER

Disease Stabilized in 45% of Patients who Completed Study through November
01/17/05 PRO-PHARMACEUTICALS COMPLETES ENROLLMENT IN PHASE I TRIAL OF DAVANAT®/5-FU IN REFRACTORY CANCER PATIENTS
12/14/04 PRO-PHARMACEUTICALS’ DAVANAT®/5-FU PHASE l TRIAL DATA TO BE PRESENTED AT ASCO GASTROINTESTINAL CANCERS SYMPOSIUM
11/30/04 Pro-Pharmaceuticals Responds to The Boston Globe Article
11/22/04 Pro-Pharmaceuticals Reports Third Quarter Results
11/18/04 Pro-Pharmaceuticals 'Sets the Record Straight' Regarding Misleading Statements Made by GlycoGenesys in News Releases
11/12/04 Dr. David Platt Gratified with Arbitrator's Decision: Continues to Control Prosecution of Modified Pectin Patent Applications
11/08/04 PRO-PHARMACEUTICALS TO PRESENT CORPORATE UPDATE AT BIO-EUROPE 2004 INTERNATIONAL PARTNERING CONFERENCE
11/03/04 PRO-PHARMACEUTICALS TO PRESENT AT MASS OPPORTUNITIES BIOTECHNOLOGY CONFERENCE
10/21/04 PRO-PHARMACEUTICALS TO PRESENT
AT TECHVEST ANNUAL HEALTHCARE CONFERENCE
10/13/04 PRO-PHARMACEUTICALS TO PRESENT
AT BIO EMERGING COMPANY INVESTOR FORUM
10/04/04 PRO-PHARMACEUTICALS PROVIDES PHASE I TRIAL UPDATE OF DAVANAT® IN REFRACTORY CANCER PATIENTS
09/30/04 PRO-PHARMACEUTICALS APPOINTS MEDICAL ADVISORY BOARD MEMBERS
09/28/04 PRO-PHARMACEUTICALS RETAINS HANIFY & KING’S LIFE SCIENCES GROUP TO PURSUE COLLABORATIONS
08/19/04 Pro-Pharmaceuticals' CEO David Platt Granted Patents for Modified Pectin Material in European Union, Canada, Australia & New Zealand
08/12/04 Pro-Pharmaceuticals Raises $6 Million
06/23/04 PRO-PHARMACEUTICALS REPORTS PHASE I FOR DAVANAT®-1 IN REFRACTORY CANCER PATIENTS IS NOW IN ITS SIXTH AND FINAL COHORT
04/07/04 Pro-Pharmaceuticals Raises $4.5 Million
03/24/04 Pro-Pharmaceuticals to Present at Company-Sponsored Carbohydrate Drug Design Symposium During National Meeting of the American Chemical Society
03/12/04 Pro-Pharmaceuticals Appoints Jerald K. Rome to Board of Directors
02/25/04 Dr. David Platt and Pro-Pharmaceuticals to Vigorously Contest Counterclaims Asserted by GlycoGenesys
01/08/04 Pro-Pharmaceuticals to Initiate a Phase II Clinical Trial of its Lead Anti-Tumor Compound DAVANAT® + 5-FU in Colorectal Cancer
12/17/03 Pro-Pharmaceuticals Names Charles Harney Chief Financial Officer
12/09/03 Pro-Pharmaceuticals Announces the Dosing of Cancer Patients at Florida Oncology Associates
11/13/03 Pro-Pharmaceuticals Issued Two U.S. Patents for its Core Carbohydrate Drug Targeting & Delivery Platforms -- CARBOSOME™ & UCLT™
10/28/03 Mass Opportunities: A Biotechnology Investment Conference, October 28, 11:30 AM, The Hilton Logan Airport, Boston
10/15/03 Pro-Pharmaceuticals To Present: `Advancing Drugs Through Glycoscience' at Techvest Healthcare & MassOpps Investment Conferences
10/3/03 Pro-Pharmaceuticals Announces $4.6 Million Private Placement Financing
9/22/03 Pro-Pharmaceuticals rang the opening bell on the American Stock Exchange
9/16/03 Animal Studies Demonstrate the Importance Pro-Pharmaceuticals’ DAVANAT® Played in Significantly Increasing the Anti-Cancer Efficacy of 5-Fluorouracil
9/15/03 Pro-Pharmaceuticals To Present: Advancing Drugs Through Glycoscience™ at UBS “Global Life Sciences” & Burrill “Life Sciences Partnering” Conferences
9/10/03 American Stock Exchange Lists Common Stock of Pro-Pharmaceuticals, Inc.
9/10/03 Pro-Pharmaceuticals’ CEO Chairs “Cancer Drugs 2003” Conference
9/10/03 Pro-Pharmaceuticals’ Common Stock Begins Trading Today on AMEX® Under the Symbol “PRW”
9/9/03 Pro-Pharmaceuticals’ Common Stock to be Traded on AMEX® Under the Symbol “PRW”
7/21/03 Pro-Pharmaceuticals Appoints Noted Carbohydrate Chemist Zbigniew J. Witczak, Ph.D. to Its Scientific Advisory Board
7/15/03 Pro-Pharmaceuticals To Host Corporate Presentations in Denver, Austin & Chicago
7/2/03 Pro-Pharmaceuticals Announces Publication of Study in Peer-Reviewed Journal Carbohydrate Research
6/24/03 Cancer Patients Injected With Pro-Pharmaceuticals’ DAVANAT®
in Phase I Clinical Trial at the Norris Cotton Cancer Center
at Dartmouth-Hitchcock Medical
6/20/03 Pro-Pharmaceuticals To Host Corporate Presentations
5/29/03 Pro-Pharmaceuticals Names Squeglia VP Investor Relations
5/14/03 Cancer Patients Injected With Pro-Pharmaceuticals’ DAVANAT® in Phase I Clinical Trial at the Ochsner Cancer Institute
4/28/03 Pro-Pharmaceuticals Receives Patent Allowance for Its Carbohydrate Linker Technology for Anti-Cancer Agents
4/14/03 Pro-Pharmaceuticals Appoints Steven Prelack to Board of Directors
4/3/03 Pro-Pharmaceuticals Reports Year End Results
3/20/03 Pro-Pharmaceuticals Appoints David Christopher as CFO
2/14/03 Cancer Patients Injected With Pro-Pharmaceuticals' DAVANAT® in Phase I Clinical Trial At Howell, New Jersey Oncology Clinics
2/6/03 Pro-Pharmaceuticals Initiates Multi-Center Clinical Trials Of DAVANAT®-1 For All Solid Tumors
1/15/03 Pro-Pharmaceuticals Completes Private Placement
1/6/03 Pro-Pharmaceuticals Expands Clinical Cancer Trial to Include Additional Solid Tumors
12/30/02 Pro-Pharmaceuticals Engages Medidata for Real-Time Electronic Data Collection in its Clinical Cancer Trial
12/19/02 Pro-Pharmaceuticals Retains PRA International for Clinical Trial In Cancer Patients
12/10/02

Pro-Pharmaceuticals Presents Overview of Carbohydrate Technology To Enhance Existing Cancer Drugs

11/15/02

Pro-Pharmaceuticals Reports Third Quarter Results

10/22/02

Pro-Pharmaceuticals Names Medical Director for Upcoming Clinical Study.
Marilyn Pike engaged as clinical development consultant to oversee firm's Phase I drug trial

10/7/02 Pro-Pharmaceuticals Appoints Mildred Christian to Board of Directors.
Expert on experimental design and government compliance to serve multiple roles with firm
9/25/02 Pro-Pharmaceuticals Featured in ‘Genetic Engineering News’ Overview of
Innovative Cancer Therapy Research
9/12/02 Pro-Pharmaceuticals Names University of Michigan Medical School Professor to Scientific Advisory Board. Expert on specialized protein-carbohydrate chemistry to consult on upcoming clinical trials.
9/5/02 Pro-Pharmaceuticals Commences Trading on NASD OTC Bulletin Board. Trading Follows FDA Approval of Human Trials With Cancer Drug Enhancement Formulation.
8/26/02 Pro-Pharmaceuticals Reports Second Quarter Results
7/29/02 Pro-Pharmaceuticals Receives FDA Approval for Phase I Clinical Trial
7/11/02 Pro-Pharmaceuticals Announces Public Reporting of Financial Results

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